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NGF reprograms metastatic melanoma to a bipotent glial-melanocyte neural crest-like precursor

Melanoma pathogenesis from normal neural crest-derived melanocytes is often fatal due to aggressive cell invasion throughout the body. The identification of signals that reprogram de-differentiated, metastatic melanoma cells to a less aggressive and stable phenotype would provide a novel strategy to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biol Open
Hauptverfasser: Kasemeier-Kulesa, Jennifer C., Romine, Morgan H., Morrison, Jason A., Bailey, Caleb M., Welch, Danny R., Kulesa, Paul M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829509/
https://ncbi.nlm.nih.gov/pubmed/29175861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.030817
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