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Epigenetically reprogramming metastatic tumor cells with an embryonic microenvironment

We have previously shown that the microenvironment of human embryonic stem cells (hESCs) is able to change and reprogram aggressive cancer cells to a less aggressive state. Some mechanisms implicated in the phenotypic changes observed after this exposure are mainly associated with the Nodal signalin...

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Détails bibliographiques
Auteurs principaux: Costa, Fabricio F, Seftor, Elisabeth A, Bischof, Jared M, Kirschmann, Dawn A, Strizzi, Luigi, Arndt, Kelly, de Fatima Bonaldo, Maria, Soares, Marcelo B, Hendrix, Mary JC
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872497/
https://ncbi.nlm.nih.gov/pubmed/20495621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.09.25
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