Orphaned ryanodine receptors in the failing heart

Heart muscle is characterized by a regular array of proteins and structures that form a repeating functional unit identified as the sarcomere. This regular structure enables tight coupling between electrical activity and Ca(2+) signaling. In heart failure, multiple cellular defects develop, includin...

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Bibliographic Details
Main Authors: Song, Long-Sheng, Sobie, Eric A., McCulle, Stacey, Lederer, W. J., Balke, C. William, Cheng, Heping
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449688/
https://ncbi.nlm.nih.gov/pubmed/16537526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509324103
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