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The Ca(2+) leak paradox and “rogue ryanodine receptors”: SR Ca(2+) efflux theory and practice
Ca(2+) efflux from the sarcoplasmic reticulum (SR) is routed primarily through SR Ca(2+) release channels (ryanodine receptors, RyRs). When clusters of RyRs are activated by trigger Ca(2+) influx through L-type Ca(2+) channels (dihydropyridine receptors, DHPR), Ca(2+) sparks are observed. Close spat...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1484520/ https://ncbi.nlm.nih.gov/pubmed/16326215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2005.06.010 |
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