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Identification of the minimal protein-folding nucleus through loop-entropy perturbations
To explore the plasticity and structural constraints of the protein-folding nucleus we have constructed through circular permutation four topological variants of the ribosomal protein S6. In effect, these topological variants represent entropy mutants with maintained spatial contacts. The proteins w...
में बचाया:
| मुख्य लेखकों: | , , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
National Academy of Sciences
2006
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1449650/ https://ncbi.nlm.nih.gov/pubmed/16505376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508863103 |
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