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Identification of the minimal protein-folding nucleus through loop-entropy perturbations

To explore the plasticity and structural constraints of the protein-folding nucleus we have constructed through circular permutation four topological variants of the ribosomal protein S6. In effect, these topological variants represent entropy mutants with maintained spatial contacts. The proteins w...

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Detalhes bibliográficos
Main Authors: Lindberg, Magnus O., Haglund, Ellinor, Hubner, Isaac A., Shakhnovich, Eugene I., Oliveberg, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449650/
https://ncbi.nlm.nih.gov/pubmed/16505376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508863103
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