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The time required for water attack at the phosphorus atom of simple phosphodiesters and of DNA

Phosphodiester linkages, including those that join the nucleotides of DNA, are highly resistant to spontaneous hydrolysis. The rate of water attack at the phosphorus atom of phosphodiesters is known only as an upper limit, based on the hydrolysis of the dimethyl phosphate anion. That reaction was fo...

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Detaylı Bibliyografya
Asıl Yazarlar: Schroeder, Gottfried K., Lad, Chetan, Wyman, Paul, Williams, Nicholas H., Wolfenden, Richard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449644/
https://ncbi.nlm.nih.gov/pubmed/16537483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510879103
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