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The time required for water attack at the phosphorus atom of simple phosphodiesters and of DNA
Phosphodiester linkages, including those that join the nucleotides of DNA, are highly resistant to spontaneous hydrolysis. The rate of water attack at the phosphorus atom of phosphodiesters is known only as an upper limit, based on the hydrolysis of the dimethyl phosphate anion. That reaction was fo...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1449644/ https://ncbi.nlm.nih.gov/pubmed/16537483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510879103 |
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