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Analysis of the Estimators of the Average Coefficient of Dominance of Deleterious Mutations

We investigate the sources of bias that affect the most commonly used methods of estimation of the average degree of dominance (h) of deleterious mutations, focusing on estimates from segregating populations. The main emphasis is on the effect of the finite size of the populations, but other sources...

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Detaylı Bibliyografya
Asıl Yazarlar: Fernández, B., García-Dorado, A., Caballero, A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448839/
https://ncbi.nlm.nih.gov/pubmed/15514075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.027706
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