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Analysis of the Estimators of the Average Coefficient of Dominance of Deleterious Mutations
We investigate the sources of bias that affect the most commonly used methods of estimation of the average degree of dominance (h) of deleterious mutations, focusing on estimates from segregating populations. The main emphasis is on the effect of the finite size of the populations, but other sources...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Genetics Society of America
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1448839/ https://ncbi.nlm.nih.gov/pubmed/15514075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.027706 |
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