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The Effect of Antagonistic Pleiotropy on the Estimation of the Average Coefficient of Dominance of Deleterious Mutations

We investigate the impact of antagonistic pleiotropy on the most widely used methods of estimation of the average coefficient of dominance of deleterious mutations from segregating populations. A proportion of the deleterious mutations affecting a given studied fitness component are assumed to have...

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Detalhes bibliográficos
Main Authors: Fernández, B., García-Dorado, A., Caballero, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2005 by the Genetics Society of America 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456129/
https://ncbi.nlm.nih.gov/pubmed/16118193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.044750
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