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Testing for Hardy-Weinberg Equilibrium in Samples With Related Individuals
When the classical χ(2) goodness-of-fit test for Hardy-Weinberg (HW) equilibrium is used on samples with related individuals, the type I error can be greatly inflated. In particular the test is inappropriate in population isolates where the individuals are related through multiple lines of descent....
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Genetics Society of America
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1448754/ https://ncbi.nlm.nih.gov/pubmed/15371359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.031617 |
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