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Reconstituting the Frequency Spectrum of Ascertained Single-Nucleotide Polymorphism Data

Most of the available SNP data have eluded valid population genetic analysis because most population genetical methods do not correctly accommodate the special discovery process used to identify SNPs. Most of the available SNP data have allele frequency distributions that are biased by the ascertain...

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Detalhes bibliográficos
Main Authors: Nielsen, Rasmus, Hubisz, Melissa J., Clark, Andrew G.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448751/
https://ncbi.nlm.nih.gov/pubmed/15371362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.031039
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