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Ascertainment bias in studies of human genome-wide polymorphism

Large-scale SNP genotyping studies rely on an initial assessment of nucleotide variation to identify sites in the DNA sequence that harbor variation among individuals. This “SNP discovery” sample may be quite variable in size and composition, and it has been well established that properties of the S...

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Autori principali: Clark, Andrew G., Hubisz, Melissa J., Bustamante, Carlos D., Williamson, Scott H., Nielsen, Rasmus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1310637/
https://ncbi.nlm.nih.gov/pubmed/16251459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.4107905
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