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End-Joining Repair of Double-Strand Breaks in Drosophila melanogaster Is Largely DNA Ligase IV Independent

Repair of DNA double-strand breaks can occur by either nonhomologous end joining or homologous recombination. Most nonhomologous end joining requires a specialized ligase, DNA ligase IV (Lig4). In Drosophila melanogaster, double-strand breaks created by excision of a P element are usually repaired b...

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Detalhes bibliográficos
Main Authors: McVey, Mitch, Radut, Dora, Sekelsky, Jeff J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448732/
https://ncbi.nlm.nih.gov/pubmed/15611176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.033902
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