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Examination of the Roles of Sgs1 and Srs2 Helicases in the Enforcement of Recombination Fidelity in Saccharomyces cerevisiae

Mutation in SGS1, which encodes the yeast homolog of the human Bloom helicase, or in mismatch repair (MMR) genes confers defects in the suppression of mitotic recombination between similar but nonidentical (homeologous) sequences. Mutational analysis of SGS1 suggests that the helicase activity is re...

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Autori principali: Spell, Rachelle Miller, Jinks-Robertson, Sue
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448721/
https://ncbi.nlm.nih.gov/pubmed/15611162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.032771
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