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Heteroduplex DNA Position Defines the Roles of the Sgs1, Srs2, and Mph1 Helicases in Promoting Distinct Recombination Outcomes

The contributions of the Sgs1, Mph1, and Srs2 DNA helicases during mitotic double-strand break (DSB) repair in yeast were investigated using a gap-repair assay. A diverged chromosomal substrate was used as a repair template for the gapped plasmid, allowing mismatch-containing heteroduplex DNA (hDNA)...

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Bibliografiska uppgifter
Huvudupphovsmän: Mitchel, Katrina, Lehner, Kevin, Jinks-Robertson, Sue
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597516/
https://ncbi.nlm.nih.gov/pubmed/23516370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003340
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