Examination of the Roles of Sgs1 and Srs2 Helicases in the Enforcement of Recombination Fidelity in Saccharomyces cerevisiae

Mutation in SGS1, which encodes the yeast homolog of the human Bloom helicase, or in mismatch repair (MMR) genes confers defects in the suppression of mitotic recombination between similar but nonidentical (homeologous) sequences. Mutational analysis of SGS1 suggests that the helicase activity is re...

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Bibliographic Details
Main Authors: Spell, Rachelle Miller, Jinks-Robertson, Sue
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2004
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448721/
https://ncbi.nlm.nih.gov/pubmed/15611162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.032771
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