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REGULATION OF NUCLEAR TRANSLOCATION OF HDAC3 BY IKBα IS REQUIRED FOR TNF-INHIBITION OF PPARγ FUNCTION
Inhibition of PPARγ function by TNF-α contributes to metabolic disorder in glucose and fatty acids under inflammation and cancer, but the molecular mechanism remains to be fully understood. In this study, we demonstrate that nuclear translocation of HDAC3 is regulated by TNF-α, and this event is req...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1447600/ https://ncbi.nlm.nih.gov/pubmed/16371367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M507784200 |
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