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REGULATION OF PPARγ FUNCTION BY TNF-α
The nuclear receptor PPARγ is a lipid sensor that regulates lipid metabolism through gene transcription. Inhibition of PPARγ activity by TNF-α is involved in pathogenesis of insulin resistance, atherosclerosis, inflammation, and cancer cachexia. PPARγ activity is regulated by TNF-α at pre-translatio...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596979/ https://ncbi.nlm.nih.gov/pubmed/18655773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.07.068 |
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