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REGULATION OF PPARγ FUNCTION BY TNF-α

The nuclear receptor PPARγ is a lipid sensor that regulates lipid metabolism through gene transcription. Inhibition of PPARγ activity by TNF-α is involved in pathogenesis of insulin resistance, atherosclerosis, inflammation, and cancer cachexia. PPARγ activity is regulated by TNF-α at pre-translatio...

詳細記述

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書誌詳細
第一著者: Ye, Jianping
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596979/
https://ncbi.nlm.nih.gov/pubmed/18655773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.07.068
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