Normal T-Cell Development and Immune Functions in TRIM-Deficient Mice

The transmembrane adaptor molecule TRIM is strongly expressed within thymus and in peripheral CD4(+) T cells. Previous studies suggested that TRIM is an integral component of the T-cell receptor (TCR)/CD3 complex and might be involved in regulating TCR cycling. To elucidate the in vivo function of T...

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Hauptverfasser: Kölsch, Uwe, Arndt, Börge, Reinhold, Dirk, Lindquist, Jonathan A., Jüling, Nicole, Kliche, Stefanie, Pfeffer, Klaus, Bruyns, Eddy, Schraven, Burkhart, Simeoni, Luca
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1447406/
https://ncbi.nlm.nih.gov/pubmed/16612002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.9.3639-3648.2006
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