An Epoxide Hydrolase Inhibitor, 12-(3-Adamantan-1-yl-ureido)dodecanoic Acid (AUDA), Reduces Ischemic Cerebral Infarct Size in Stroke-Prone Spontaneously Hypertensive Rats

Soluble epoxide hydrolase (sEH) inhibitors have been demonstrated to have cardiovascular protective actions. This hydrolase enzyme converts fatty acid epoxides to their corresponding diols, and this conversion can alter the biologic activity of these metabolites. We hypothesized that 12-(3-adamantan...

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Bibliografiset tiedot
Päätekijät: Dorrance, Anne M., Rupp, Nicole, Pollock, David M., Newman, John W., Hammock, Bruce D., Imig, John D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2005
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1444897/
https://ncbi.nlm.nih.gov/pubmed/16306811
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