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Soluble epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)-dodecanoic acid, represses human aortic smooth muscle cell proliferation and migration by regulating cell death pathways via the mTOR signaling

The soluble epoxide hydrolase (sEH) is a molecule necessary for the metabolism of endogenous constituents implicated in blood pressure regulation and vascular inflammation. Scientific evidences indicate that sEH inhibitors such as 12-(3-Adamantan-1-yl-ureido)-dodecanoic acid (AUDA) could be a possib...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Li, Shao-Hua, Zhao, Peng, Tian, Hong-Bo, Chen, Liang-Hua, Cui, Lian-Qun
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965454/
https://ncbi.nlm.nih.gov/pubmed/31966695
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