An Orally Active Epoxide Hydrolase Inhibitor Lowers Blood Pressure and Provides Renal Protection in Salt-Sensitive Hypertension

The present study tested the hypothesis that increasing epoxyeicosatrienoic acids by inhibition of soluble epoxide hydrolase (sEH) would lower blood pressure and ameliorate renal damage in salt-sensitive hypertension. Rats were infused with angiotensin and fed a normal-salt diet or an 8% NaCl diet f...

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Detaylı Bibliyografya
Asıl Yazarlar: Imig, John D., Zhao, Xueying, Zaharis, Constantine Z., Olearczyk, Jeffrey J., Pollock, David M., Newman, John W., Kim, In-Hae, Watanabe, Takaho, Hammock, Bruce D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2005
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1444888/
https://ncbi.nlm.nih.gov/pubmed/16157792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.HYP.0000176237.74820.75
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