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Tip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progression
The histone acetyl transferase Tip60 (HTATIP) belongs to a multimolecular complex involved in the cellular response to DNA damage. Tip60 participates in cell cycle arrest following DNA damage by allowing p53 to activate p21CIP (p21) expression. We show here that Tip60 and the E1A-associated p400 pro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440826/ https://ncbi.nlm.nih.gov/pubmed/16601686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601066 |
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