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Control of genetic stability by a new heterochromatin compaction pathway involving the Tip60 histone acetyltransferase
Pericentric heterochromatin is a highly compacted structure required for accurate chromosome segregation in mitosis. In mammals, it relies on methylation of histone H3K9 by Suv39H enzymes, which provides a docking site for HP1 proteins, therefore mediating heterochromatin compaction. Here we show th...
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Publicado no: | Mol Biol Cell |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Cell Biology
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4750920/ https://ncbi.nlm.nih.gov/pubmed/26700317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-05-0316 |
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