Axin is a scaffold protein in TGF-β signaling that promotes degradation of Smad7 by Arkadia

TGF-β signaling involves a wide array of signaling molecules and multiple controlling events. Scaffold proteins create a functional proximity of signaling molecules and control the specificity of signal transduction. While many components involved in the TGF-β pathway have been elucidated, little is...

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Autori principali: Liu, Wei, Rui, Hongliang, Wang, Jifeng, Lin, Shuyong, He, Ying, Chen, Mingliang, Li, Qinxi, Ye, Zhiyun, Zhang, Suping, Chan, Siu Chiu, Chen, Ye-Guang, Han, Jiahuai, Lin, Sheng-Cai
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440825/
https://ncbi.nlm.nih.gov/pubmed/16601693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601057
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