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Entropy-Driven Genome Organization

DNA and RNA polymerases active on bacterial and human genomes in the crowded environment of a cell are modeled as beads spaced along a string. Aggregation of the large polymerizing complexes increases the entropy of the system through an increase in entropy of the many small crowding molecules; this...

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Autors principals: Marenduzzo, Davide, Micheletti, Cristian, Cook, Peter R.
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440752/
https://ncbi.nlm.nih.gov/pubmed/16500976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.077685
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