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Transcription-driven genome organization: a model for chromosome structure and the regulation of gene expression tested through simulations
Current models for the folding of the human genome see a hierarchy stretching down from chromosome territories, through A/B compartments and topologically-associating domains (TADs), to contact domains stabilized by cohesin and CTCF. However, molecular mechanisms underlying this folding, and the way...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6212781/ https://ncbi.nlm.nih.gov/pubmed/30239812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky763 |
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