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Statistical Evaluation of Ion-Channel Gating Models Based on Distributions of Log-Likelihood Ratios
The distributions of log-likelihood ratios (ΔLL) obtained from fitting ion-channel dwell-time distributions with nested pairs of gating models (Ξ, full model; Ξ(R), submodel) were studied both theoretically and using simulated data. When Ξ is true, ΔLL is asymptotically normally distributed with pre...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Biophysical Society
2006
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440734/ https://ncbi.nlm.nih.gov/pubmed/16461404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.075135 |
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