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Rotavirus Spike Protein VP4 Binds to and Remodels Actin Bundles of the Epithelial Brush Border into Actin Bodies

We demonstrate here that VP4, a rotaviral protein, is able to specifically bind to bundled actin microfilaments that are subsequently profoundly remodeled into actin bodies. These cytoplasmic actin bodies do not localize within identified intracellular compartments. VP4-induced actin remodeling is s...

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Bibliografske podrobnosti
Main Authors: Gardet, Agnès, Breton, Michelyne, Fontanges, Philippe, Trugnan, Germain, Chwetzoff, Serge
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440440/
https://ncbi.nlm.nih.gov/pubmed/16571811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.8.3947-3956.2006
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