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The C Terminus of Rotavirus VP4 Protein Contains an Actin Binding Domain Which Requires Cooperation with the Coiled-Coil Domain for Actin Remodeling

The interactions between viruses and actin cytoskeleton have been widely studied. We showed that rotaviruses remodel microfilaments in intestinal cells and demonstrated that this was due to the VP4 spike protein. Microfilaments mainly occur in the apical domain of infected polarized enterocytes and...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Condemine, Wilfried, Eguether, Thibaut, Couroussé, Nathalie, Etchebest, Catherine, Gardet, Agnes, Trugnan, Germain, Chwetzoff, Serge
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288328/
https://ncbi.nlm.nih.gov/pubmed/30333172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01598-18
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