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The C Terminus of Rotavirus VP4 Protein Contains an Actin Binding Domain Which Requires Cooperation with the Coiled-Coil Domain for Actin Remodeling

The interactions between viruses and actin cytoskeleton have been widely studied. We showed that rotaviruses remodel microfilaments in intestinal cells and demonstrated that this was due to the VP4 spike protein. Microfilaments mainly occur in the apical domain of infected polarized enterocytes and...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Condemine, Wilfried, Eguether, Thibaut, Couroussé, Nathalie, Etchebest, Catherine, Gardet, Agnes, Trugnan, Germain, Chwetzoff, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288328/
https://ncbi.nlm.nih.gov/pubmed/30333172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01598-18
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