The C Terminus of Rotavirus VP4 Protein Contains an Actin Binding Domain Which Requires Cooperation with the Coiled-Coil Domain for Actin Remodeling

The interactions between viruses and actin cytoskeleton have been widely studied. We showed that rotaviruses remodel microfilaments in intestinal cells and demonstrated that this was due to the VP4 spike protein. Microfilaments mainly occur in the apical domain of infected polarized enterocytes and...

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Bibliographic Details
Published in:J Virol
Main Authors: Condemine, Wilfried, Eguether, Thibaut, Couroussé, Nathalie, Etchebest, Catherine, Gardet, Agnes, Trugnan, Germain, Chwetzoff, Serge
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288328/
https://ncbi.nlm.nih.gov/pubmed/30333172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01598-18
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