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Rotavirus Spike Protein VP4 Binds to and Remodels Actin Bundles of the Epithelial Brush Border into Actin Bodies

We demonstrate here that VP4, a rotaviral protein, is able to specifically bind to bundled actin microfilaments that are subsequently profoundly remodeled into actin bodies. These cytoplasmic actin bodies do not localize within identified intracellular compartments. VP4-induced actin remodeling is s...

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Detalhes bibliográficos
Main Authors: Gardet, Agnès, Breton, Michelyne, Fontanges, Philippe, Trugnan, Germain, Chwetzoff, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440440/
https://ncbi.nlm.nih.gov/pubmed/16571811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.8.3947-3956.2006
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