Intrarectal Immunization with Rotavirus 2/6 Virus-Like Particles Induces an Antirotavirus Immune Response Localized in the Intestinal Mucosa and Protects against Rotavirus Infection in Mice

Rotavirus (RV) is the main etiological agent of severe gastroenteritis in infants, and vaccination seems the most effective way to control the disease. Recombinant rotavirus-like particles composed of the viral protein 6 (VP6) and VP2 (2/6-VLPs) have been reported to induce protective immunity in mi...

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Hlavní autoři: Agnello, Davide, Hervé, Christine A., Lavaux, Amandine, Darniot, Magali, Guillon, Patrice, Charpilienne, Annie, Pothier, Pierre
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440434/
https://ncbi.nlm.nih.gov/pubmed/16571799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.8.3823-3832.2006
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