Rectal Immunization with Rotavirus Virus-Like Particles Induces Systemic and Mucosal Humoral Immune Responses and Protects Mice against Rotavirus Infection

To evaluate whether the rectal route of immunization may be used to provide appropriate protection against enteric pathogens such as rotaviruses (RV), we studied the antibody response and the protection induced by rectal immunization of mice with RV virus-like particles (VLP). For this purpose, 6-we...

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Detalhes bibliográficos
Main Authors: Parez, Nathalie, Fourgeux, Cynthia, Mohamed, Ali, Dubuquoy, Catherine, Pillot, Mathieu, Dehee, Axelle, Charpilienne, Annie, Poncet, Didier, Schwartz-Cornil, Isabelle, Garbarg-Chenon, Antoine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367137/
https://ncbi.nlm.nih.gov/pubmed/16439532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.1752-1761.2006
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