Rotavirus Anti-VP6 Secretory Immunoglobulin A Contributes to Protection via Intracellular Neutralization but Not via Immune Exclusion

Immunoglobulin A (IgA) monoclonal antibodies (MAbs) directed at the conserved inner core protein VP6 of rotavirus, such as the IgA7D9 MAb, provide protective immunity in adult and suckling mice when delivered systemically. While these antibodies do not have traditional in vitro neutralizing activity...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Corthésy, Blaise, Benureau, Yann, Perrier, Clémentine, Fourgeux, Cynthia, Parez, Nathalie, Greenberg, Harry, Schwartz-Cornil, Isabelle
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2006
Aiheet:
Pathogenesis and Immunity
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1641769/
https://ncbi.nlm.nih.gov/pubmed/16956954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00927-06
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