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Rectal Immunization with Rotavirus Virus-Like Particles Induces Systemic and Mucosal Humoral Immune Responses and Protects Mice against Rotavirus Infection

To evaluate whether the rectal route of immunization may be used to provide appropriate protection against enteric pathogens such as rotaviruses (RV), we studied the antibody response and the protection induced by rectal immunization of mice with RV virus-like particles (VLP). For this purpose, 6-we...

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Autori principali: Parez, Nathalie, Fourgeux, Cynthia, Mohamed, Ali, Dubuquoy, Catherine, Pillot, Mathieu, Dehee, Axelle, Charpilienne, Annie, Poncet, Didier, Schwartz-Cornil, Isabelle, Garbarg-Chenon, Antoine
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367137/
https://ncbi.nlm.nih.gov/pubmed/16439532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.1752-1761.2006
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