Enhanced Production of Recombinant Proteins in Escherichia coli by Filamentation Suppression

During growth of high-cell-density cultures of Escherichia coli, overproduction of recombinant proteins often results in increased stress response, cell filamentation, and growth cessation. Filamentation of cells consequently lowers final achievable cell concentration and productivity of the target...

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Bibliografische gegevens

Gepubliceerd in:	Appl Environ Microbiol
Hoofdauteurs:	Jeong, Ki Jun, Lee, Sang Yup
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 2003
Onderwerpen:	Physiology and Biotechnology
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC143674/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12571061/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.2.1295-1298.2003
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