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Enhanced Production of Recombinant Proteins in Escherichia coli by Filamentation Suppression

During growth of high-cell-density cultures of Escherichia coli, overproduction of recombinant proteins often results in increased stress response, cell filamentation, and growth cessation. Filamentation of cells consequently lowers final achievable cell concentration and productivity of the target...

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Vydáno v:Appl Environ Microbiol
Hlavní autoři: Jeong, Ki Jun, Lee, Sang Yup
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC143674/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12571061/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.2.1295-1298.2003
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