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Hyperglycemia Potentiates H(2)O(2) Production in Adipocytes and Enhances Insulin Signal Transduction: Potential Role for Oxidative Inhibition of Thiol-Sensitive Protein-Tyrosine Phosphatases
Insulin signal transduction in adipocytes is accompanied by a burst of cellular hydrogen peroxide (H(2)O(2) facilitates insulin signaling by inhibiting thiol-dependent protein-tyrosine phosphatases (PTPs)) that are negative regulators of insulin action. As hyperglycemia is associated with increased...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1435729/ https://ncbi.nlm.nih.gov/pubmed/15889998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2005.7.526 |
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