Generation of Helicobacter pylori Ghosts by PhiX Protein E-Mediated Inactivation and Their Evaluation as Vaccine Candidates

Bacterial ghosts are empty cell envelopes, which may be generated by the controlled expression of the PhiX174 lysis gene E in gram-negative bacteria to obtain vaccine candidates. We describe here the application of this technology to Helicobacter pylori. The lysis gene cassette was cloned into an Es...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Principais autores:	Panthel, Klaus, Jechlinger, Wolfgang, Matis, Alexander, Rohde, Manfred, Szostak, Michael, Lubitz, Werner, Haas, Rainer
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2003
Assuntos:	Microbial Immunity and Vaccines
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC143412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12496155/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.1.109-116.2003
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