γ-Glutamyltransferase Is a Helicobacter pylori Virulence Factor but Is Not Essential for Colonization

The contribution of glutamyl transpeptidase (GGT) (γ-glutamyltransferase [EC 2. 3. 2. 2]) to Helicobacter pylori virulence was investigated in piglets and mice using GGT-deficient isogenic strains. All animals became colonized. However, the bacterial load was significantly lower for mutant bacteria...

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Detalhes bibliográficos
Main Authors: McGovern, K. J., Blanchard, T. G., Gutierrez, J. A., Czinn, S. J., Krakowka, S., Youngman, P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98487/
https://ncbi.nlm.nih.gov/pubmed/11349094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.6.4168-4173.2001
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