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Generation of Helicobacter pylori Ghosts by PhiX Protein E-Mediated Inactivation and Their Evaluation as Vaccine Candidates

Bacterial ghosts are empty cell envelopes, which may be generated by the controlled expression of the PhiX174 lysis gene E in gram-negative bacteria to obtain vaccine candidates. We describe here the application of this technology to Helicobacter pylori. The lysis gene cassette was cloned into an Es...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Panthel, Klaus, Jechlinger, Wolfgang, Matis, Alexander, Rohde, Manfred, Szostak, Michael, Lubitz, Werner, Haas, Rainer
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC143412/
https://ncbi.nlm.nih.gov/pubmed/12496155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.1.109-116.2003
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