MprF-Mediated Lysinylation of Phospholipids in Staphylococcus aureus Leads to Protection against Oxygen-Independent Neutrophil Killing

Staphylococcus aureus achieves resistance to defensins and similar cationic antimicrobial peptides (CAMPs) by modifying anionic membrane lipids via MprF with l-lysine, which leads to repulsion of these host defense molecules. S. aureus ΔmprF, which lacks the modification, was very efficiently killed...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kristian, Sascha A., Dürr, Manuela, Van Strijp, Jos A. G., Neumeister, Birgid, Peschel, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC143157/
https://ncbi.nlm.nih.gov/pubmed/12496209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.1.546-549.2003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados