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Cleavage of Antigen-Bound Immunoglobulin G by SpeB Contributes to Streptococcal Persistence in Opsonizing Blood

Group A streptococci (GAS) express a superantigen, SpeB, having cysteine protease activity. SpeB exhibits several properties that might contribute to virulence, the most recently discovered being the ability to cleave immunoglobulin G (IgG) in a manner similar to that of papain. In the present study...

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Autores principales: Eriksson, Anna, Norgren, Mari
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC143146/
https://ncbi.nlm.nih.gov/pubmed/12496168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.1.211-217.2003
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