Activation of Transferrin Receptor 1 by c-Myc Enhances Cellular Proliferation and Tumorigenesis

Overexpression of transferrin receptor 1 (TFRC1), a major mediator of iron uptake in mammalian cells, is a common feature of human malignancies. Therapeutic strategies designed to interfere with tumor iron metabolism have targeted TFRC1. The c-Myc oncogenic transcription factor stimulates proliferat...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: O'Donnell, Kathryn A., Yu, Duonan, Zeller, Karen I., Kim, Jung-whan, Racke, Frederick, Thomas-Tikhonenko, Andrei, Dang, Chi V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2006
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430295/
https://ncbi.nlm.nih.gov/pubmed/16508012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.6.2373-2386.2006
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