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Normal Cells, but Not Cancer Cells, Survive Severe Plk1 Depletion
We previously reported the phenotype of depletion of polo-like kinase 1 (Plk1) using RNA interference (RNAi) and showed that p53 is stabilized in Plk1-depleted cancer cells. In this study, we further analyzed the Plk1 depletion-induced phenotype in both cancer cells and primary cells. The vector-bas...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1430287/ https://ncbi.nlm.nih.gov/pubmed/16507989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.6.2093-2108.2006 |
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