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Mefloquine Induces Dose-Related Neurological Effects in a Rat Model

Mefloquine is one of the drugs approved by the FDA for malaria chemoprophylaxis. Mefloquine is also approved for the treatment of malaria and is widely used for this purpose in combination with artesunate. However, the clinical utility of the compound has been compromised by reports of adverse neuro...

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Detalhes bibliográficos
Main Authors: Dow, G., Bauman, R., Caridha, D., Cabezas, M., Du, F., Gomez-Lobo, R., Park, M., Smith, K., Cannard, K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426433/
https://ncbi.nlm.nih.gov/pubmed/16495267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.3.1045-1053.2006
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