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The Power to Detect Disease Associations with Mitochondrial DNA Haplogroups

Genetic variation of mitochondrial DNA (mtDNA) has been linked to a number of multifactorial diseases, but there is currently no tool available to predict the optimal size for these investigations. We used a simulation-based (Monte Carlo) permutation test to generate power curves for European mtDNA...

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Detalhes bibliográficos
Main Authors: Samuels, David C., Carothers, Andrew D., Horton, Robin, Chinnery, Patrick F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1424681/
https://ncbi.nlm.nih.gov/pubmed/16532401
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