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Determinants of conformational dimerization of Mad2 and its inhibition by p31(comet)
The spindle assembly checkpoint (SAC) monitors chromosome attachment to spindle microtubules. SAC proteins operate at kinetochores, scaffolds mediating chromosome-microtubule attachment. The ubiquitous SAC constituents Mad1 and Mad2 are recruited to kinetochores in prometaphase. Mad2 sequesters Cdc2...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1422169/ https://ncbi.nlm.nih.gov/pubmed/16525508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601033 |
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